Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | KLK1 | P06870 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783150 | 0.82 | F2 (0.52) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL1196550 | 0.81 | CYP4Z1 (0.50) | PAMKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1197040 | 0.81 | HDAC4 (0.40) | POLB | |
| SCHEMBL28033137 | 0.77 | PAM (0.57) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| Trifluoroacetic Acid SCHEMBL29624219 | 0.76 | PAM (0.55) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL10434626 | 0.75 | ALDH1A1 (0.42) | PAMPOLBKMT2AALDH1A1GAA | |
| SCHEMBL10434622 | 0.74 | ALDH1A1 (0.42) | PAMKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL11410601 | 0.74 | SMN1; SMN2 (0.40) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL1196446 | 0.73 | CYP4F2 (0.58) | KMT2AALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL3160145 | 0.73 | SMN1; SMN2 (0.60) | POLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118175998-A | Inhalable protease inhibitors for the prevention and/or treatment of fibrotic autoimmune or inflammatory lung diseases | 阿尔伯特-路德维希-弗莱堡大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-116710128-A | Antibodies that specifically bind to SARSCOV2 spike protein and methods of making same | EW集团有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115666550-A | Cysteine protease inhibitors for the prevention and/or treatment of coronaviruses | 阿尔伯特-路德维希-弗莱堡大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |