Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 13/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687614 | 0.86 | DDR1 (0.34) | S1PR1DDR1TRPV4 | |
| SCHEMBL20687612 | 0.84 | S1PR1 (0.37) | S1PR1DDR1GRM2SDHBELANE | |
| SCHEMBL20687611 | 0.84 | DDR1 (0.33) | DDR1 | |
| SCHEMBL19209956 | 0.84 | DDR1 (0.34) | DDR1 | |
| SCHEMBL20687619 | 0.83 | DDR1 (0.37) | DDR1 | |
| SCHEMBL19209949 | 0.81 | DDR1 (0.36) | DDR1 | |
| SCHEMBL19250865 | 0.81 | DDR1 (0.35) | DDR1 | |
| SCHEMBL19209964 | 0.79 | DDR1 (0.37) | DDR1 | |
| SCHEMBL19209951 | 0.79 | KCNH2 (0.37) | DDR1 | |
| SCHEMBL20687615 | 0.78 | DDR1 (0.36) | S1PR1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-31 | — | — | US | disclosed |
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-31 | — | — | US | disclosed |
| EP-3411373-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017134066-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017134066-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | S1PR1 2431/4885DDR1 4470/4885GRM2 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.