Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687617 | 0.86 | S1PR1 (0.35) | S1PR1DDR1ELANE | |
| SCHEMBL19209962 | 0.84 | S1PR1 (0.34) | S1PR1DDR1GRM2ELANESDHB | |
| SCHEMBL19209967 | 0.83 | SMN1; SMN2 (0.33) | DDR1EGLN1USP1 | |
| SCHEMBL20687613 | 0.83 | GRN (0.35) | DDR1EGLN1USP1 | |
| SCHEMBL19250870 | 0.81 | DDR1 (0.36) | DDR1USP1 | |
| SCHEMBL19250869 | 0.81 | DDR1 (0.33) | DDR1SDHBUSP1 | |
| SCHEMBL19250862 | 0.80 | DDR1 (0.33) | DDR1 | |
| SCHEMBL19209943 | 0.80 | KCNH2 (0.36) | S1PR1DDR1SDHBEGLN1USP1 | |
| SCHEMBL20687621 | 0.78 | DDR1 (0.34) | S1PR1DDR1EGLN1USP1 | |
| SCHEMBL19250864 | 0.78 | DDR1 (0.32) | S1PR1DDR1EGLN1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | S1PR1 2431/4885DDR1 4470/4885GRM2 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.