Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250868 | 0.86 | HSD17B10 (0.33) | SMN1; SMN2ALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL19250870 | 0.85 | DDR1 (0.36) | DDR1USP1 | |
| SCHEMBL20687613 | 0.85 | GRN (0.35) | SMN1; SMN2ALDH1A1HPGDKDM4EDDR1 | |
| SCHEMBL19250869 | 0.85 | DDR1 (0.33) | DDR1USP1 | |
| SCHEMBL19250862 | 0.84 | DDR1 (0.33) | DDR1 | |
| SCHEMBL20687617 | 0.83 | S1PR1 (0.35) | DDR1 | |
| SCHEMBL20687612 | 0.83 | S1PR1 (0.37) | DDR1USP1EGLN1 | |
| SCHEMBL19209946 | 0.83 | PIK3CA (0.33) | SMN1; SMN2ALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL19209956 | 0.82 | DDR1 (0.34) | SMN1; SMN2ALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL19209943 | 0.82 | KCNH2 (0.36) | DDR1USP1PIK3CAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-31 | — | — | US | disclosed |
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-31 | — | — | US | disclosed |
| EP-3411373-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017134066-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-10 | — | — | WO | disclosed |
| US-20160102146-A1 | ANTI-LGR5 ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH, INC. (US) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102146-A1 | ANTI-LGR5 ANTIBODIES AND IMMUNOCONJUGATES | EPCAM, CD44, CD63 | SMN1; SMN2 4696/4885ALDH1A1 621/4885HPGD 3580/4885 |
| US-20190031667-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | SMN1; SMN2 309/4885ALDH1A1 376/4885HPGD 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.