Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210369 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1GAAALOX12MEN1 | |
| SCHEMBL7987385 | 0.85 | NPC1 (0.31) | — | |
| SCHEMBL28814181 | 0.81 | NPC1 (0.33) | KDM4E | |
| SCHEMBL8466920 | 0.75 | — | — | |
| SCHEMBL6810034 | 0.75 | GABRA1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15066993 | 0.75 | HPGD (0.37) | KDM4EALDH1A1GAAALOX12MEN1 | |
| SCHEMBL15066995 | 0.75 | HPGD (0.37) | KDM4EALDH1A1GAAALOX12MEN1 | |
| SCHEMBL15067561 | 0.72 | ALDH1A1 (0.33) | KDM4EALDH1A1ALOX12HPGDGFER | |
| SCHEMBL15067562 | 0.72 | ALDH1A1 (0.33) | KDM4EALDH1A1ALOX12HPGDGFER | |
| SCHEMBL177278 | 0.72 | GABRA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2921493-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | BAYER IP GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |