SCHEMBL7987385

SCHEMBL7987385

CCc1[c]c(C=NN=Cc2[c]c(CC)ccc2)ccc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19210370 0.85 KDM4E (0.33)
SCHEMBL19210369 0.85 KDM4E (0.33)
SCHEMBL8466920 0.78
SCHEMBL6810034 0.78 GABRA1 (0.32)
SCHEMBL177278 0.75 GABRA1 (0.38)
SCHEMBL6840967 0.70
SCHEMBL177368 0.67
SCHEMBL28322651 0.67 GABRA1 (0.37)
SCHEMBL27982344 0.66 SRC (0.31)
SCHEMBL11745960 0.66 GABRA1 (0.46) NPC1CASP3SENP8SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4942132-A LEUCO DYES, HYDROPEROXIDE, PROTOPORPHRINS, AMINE LITMUS CONCEPTS, INC. (US) 1990-07-17 US claimed
EP-0204833-A4 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS. LAWRENCE PAUL J 1988-02-03 EP claimed
EP-0204833-A1 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS LAWRENCE, Paul J. (US) 1986-12-17 EP claimed
WO-1986003585-A1 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS LAWRENCE PAUL J 1986-06-19 WO claimed
WO-2000010008-A1 SELF-CONTAINED SYSTEM AND METHOD FOR TESTING FOR FECAL OCCULT BLOOD DIAGNOSTICA, INC. (US) 2000-02-24 WO disclosed
EP-0530852-A1 Fecal occult blood test reagents and methods LAWRENCE, Paul J. (US) 1993-03-10 EP disclosed
EP-0267952-A4 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS. LAWRENCE PAUL J 1989-06-27 EP disclosed
EP-0267952-A1 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS LAWRENCE, Paul J. (US) 1988-05-25 EP disclosed
WO-1987007718-A1 FECAL OCCULT BLOOD TEST REAGENTS AND METHODS LAWRENCE PAUL J 1987-12-17 WO disclosed