Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210475 | 0.91 | FFAR4 (0.33) | CTSA | |
| SCHEMBL19210491 | 0.90 | AKR1C3 (0.38) | CTSAPPARDIKBKBAKR1C3AKR1C2 | |
| SCHEMBL19210450 | 0.90 | FFAR4 (0.35) | PPARD | |
| SCHEMBL19210420 | 0.88 | PTGS2 (0.34) | CTSAPTGS2PTGDR2PTGS1 | |
| SCHEMBL19210513 | 0.88 | PTPN1 (0.34) | PPARDIKBKB | |
| SCHEMBL19210439 | 0.87 | SCN9A (0.34) | PTGDR2 | |
| SCHEMBL19210396 | 0.86 | S1PR1 (0.35) | TP53TPH1 | |
| SCHEMBL13734082 | 0.83 | PPARD (0.37) | PPARDTP53IKBKBPTGDR2HTT | |
| SCHEMBL19210393 | 0.82 | MAPT (0.35) | CTSAPPARDIKBKBPTGS2PTGDR2 | |
| SCHEMBL15674929 | 0.82 | IKBKB (0.36) | CTSATP53IKBKBPTGDR2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |