Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210474 | 0.91 | RXRA (0.34) | CTSAPTGDR2FFAR4 | |
| SCHEMBL19210489 | 0.90 | RXRA (0.39) | CTSALMNAPPARDALDH1A1IKBKB | |
| SCHEMBL19210449 | 0.90 | FFAR4 (0.36) | CTSAFFAR4PPARD | |
| SCHEMBL13731829 | 0.90 | IKBKB (0.34) | MAPTGAACTSAPTGDR2LMNA | |
| SCHEMBL19210419 | 0.89 | CTSA (0.34) | CTSAPTGDR2PTGS2PTGS1 | |
| SCHEMBL13734658 | 0.88 | PTPN1 (0.34) | PTGDR2FFAR4PPARDIKBKB | |
| SCHEMBL19210438 | 0.88 | IMPDH2 (0.33) | CTSAPTGDR2FFAR4 | |
| SCHEMBL13731962 | 0.87 | IKBKB (0.32) | MAPTGAACTSALMNAALDH1A1 | |
| SCHEMBL19210395 | 0.86 | S1PR1 (0.36) | LMNA | |
| SCHEMBL13734080 | 0.85 | IKBKB (0.36) | MAPTGAACTSAPTGDR2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |