Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | TPH1 | P17752 | 4/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210475 | 0.87 | FFAR4 (0.33) | FPR2FFAR4 | |
| SCHEMBL19210394 | 0.86 | CTSA (0.33) | TPH1TP53 | |
| SCHEMBL19210420 | 0.85 | PTGS2 (0.34) | — | |
| SCHEMBL19210513 | 0.85 | PTPN1 (0.34) | S1PR1FFAR4 | |
| SCHEMBL19210439 | 0.84 | SCN9A (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL19210395 | 0.84 | S1PR1 (0.36) | S1PR1TPH1LMNATSHRNFKB1 | |
| SCHEMBL19210450 | 0.83 | FFAR4 (0.35) | FFAR4 | |
| SCHEMBL13733841 | 0.83 | LMNA (0.33) | S1PR1TPH1AOC3CTSDP2RX3 | |
| SCHEMBL13736704 | 0.81 | LMNA (0.35) | S1PR1TPH1AOC3CTSDLMNA | |
| SCHEMBL19210491 | 0.80 | AKR1C3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |