Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210490 | 0.92 | PTGDR2 (0.38) | FFAR4PTGDR2CTSADHODHFFAR1 | |
| SCHEMBL19210474 | 0.91 | RXRA (0.34) | RXRARXRBRXRGFFAR4PTGDR2 | |
| SCHEMBL13731632 | 0.89 | SCN9A (0.36) | PTGDR2CTSADHODHFPR2SCN9A | |
| SCHEMBL19210454 | 0.88 | P2RX3 (0.33) | DHODHFPR2SCN9A | |
| SCHEMBL13731867 | 0.85 | SCN9A (0.33) | PTGDR2CTSAFPR2SCN9A | |
| SCHEMBL13734612 | 0.84 | PPARG (0.41) | PTGDR2CTSADHODHFPR2SCN9A | |
| SCHEMBL13733428 | 0.83 | FPR2 (0.33) | CTSAFPR2SCN9A | |
| SCHEMBL15711729 | 0.83 | SCN9A (0.33) | PTGDR2CTSAFPR2SCN9A | |
| SCHEMBL13731834 | 0.82 | FPR2 (0.32) | PTGDR2CTSAFPR2SCN9A | |
| SCHEMBL13734658 | 0.82 | PTPN1 (0.34) | RXRARXRBRXRGFFAR4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |