Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335605 | 0.94 | ACE (0.43) | ACEACE2DPP4FKBP1AGAA | |
| SCHEMBL2226082 | 0.87 | DPP4 (0.46) | DPP4FKBP1AITGB3ITGA2BF2 | |
| SCHEMBL9603823 | 0.84 | DPP4 (0.44) | DPP4FKBP1AITGB3ITGA2BITGA4 | |
| SCHEMBL11875888 | 0.81 | KMT2A (0.46) | DPP4FKBP1AITGB3ITGA2BALDH1A1 | |
| SCHEMBL14336163 | 0.81 | DPP4 (0.45) | DPP4FKBP1AITGB3ITGA2BF2 | |
| SCHEMBL4336585 | 0.80 | ACE (0.43) | ACEACE2ITGA4ITGB1F2 | |
| SCHEMBL7853147 | 0.78 | DPP4 (0.41) | DPP4F2 | |
| SCHEMBL9577364 | 0.78 | DPP4 (0.41) | DPP4F2 | |
| SCHEMBL15524993 | 0.78 | DPP4 (0.41) | DPP4F2 | |
| SCHEMBL28899291 | 0.78 | DPP4 (0.39) | DPP4ITGB3ITGA2BITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723886-B1 | DETERMINATION OF DIRECT THROMBIN INHIBITORS IN SERUM OR URINE | DOASENSE GMBH (DE) | 2017-08-16 | — | — | EP | claimed |