Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 11/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226082 | 0.97 | DPP4 (0.46) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL28899291 | 0.92 | DPP4 (0.39) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL14336163 | 0.92 | DPP4 (0.45) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL12955580 | 0.91 | F2 (0.44) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12955380 | 0.89 | DPP4 (0.42) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL5597236 | 0.86 | DPP4 (0.40) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL9396036 | 0.85 | DPP4 (0.43) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3239444 | 0.85 | F2 (0.46) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19210494 | 0.84 | ACE (0.44) | DPP4ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8469063 | 0.84 | F2 (0.35) | DPP4F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190862-A | Peptide modified compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5108890-A | Diagnostic agents for determining peptide bond-cleaving enzymes; measuring light absorbed by liberated colored materials | BOEHRINGER MANNHEIM GMBH (DE) | 1992-04-28 | — | — | US | disclosed |