SCHEMBL2226082

SCHEMBL2226082

Cc1ccc(S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.46
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
F2 P00734 11/20 0.41
PRSS1 P07477 8/20 0.41
PRSS2 P07478 8/20 0.41
PRSS3 P35030 8/20 0.41
FKBP1A P62942 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9603823 0.97 DPP4 (0.44) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL14336163 0.94 DPP4 (0.45) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL12955380 0.91 DPP4 (0.42) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL28899291 0.91 DPP4 (0.39) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL5597236 0.89 DPP4 (0.40) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL12955580 0.88 F2 (0.44) DPP4F2PRSS1PRSS2PRSS3
SCHEMBL9396036 0.88 DPP4 (0.43) DPP4F2PRSS1PRSS2PRSS3
SCHEMBL3239444 0.88 F2 (0.46) DPP4F2PRSS1PRSS2PRSS3
SCHEMBL19210494 0.87 ACE (0.44) DPP4ITGB3ITGA2BF2PRSS1
SCHEMBL10866479 0.86 F2 (0.37) DPP4ITGB3ITGA2BF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132678-A1 QUALITATIVE TEST FOR DIRECT ORAL ANTICOAGULANTS (DOACS) F. HOFFMANN-LA ROCHE AG (CH) 2025-06-26 WO claimed
CN-118516444-A Reaction reagent for detecting prothrombin time by electrochemical method, test card and application 杭州安旭生物科技股份有限公司 2024-08-20 CN claimed
EP-3955003-B1 SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES ABBOTT POINT OF CARE INC (US) 2023-06-21 EP claimed
EP-3198281-B1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS ABBOTT POINT OF CARE INC (US) 2023-01-25 EP claimed
EP-3955003-A1 SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES Abbott Point Of Care Inc (US) 2022-02-16 EP claimed
WO-2025132678-A1 QUALITATIVE TEST FOR DIRECT ORAL ANTICOAGULANTS (DOACS) F. HOFFMANN-LA ROCHE AG (CH) 2025-06-26 WO disclosed
CN-222866693-U Test card for prothrombin time of blood sample, blood detection device and system 杭州安旭生物科技股份有限公司 2025-05-13 CN disclosed
CN-118516444-A Reaction reagent for detecting prothrombin time by electrochemical method, test card and application 杭州安旭生物科技股份有限公司 2024-08-20 CN disclosed
CN-109507260-B Electrochemical detection chip, electrochemical sensor, and preparation methods and applications thereof 中国科学院苏州生物医学工程技术研究所 2024-07-05 CN disclosed
EP-3802550-B1 NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING INST NAT SANTE RECH MED (FR) 2023-12-27 EP disclosed
US-11767333-B2 Benzimidamides compounds comprising an oxaborinin ring INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2023-09-26 US disclosed
CN-112638532-B Cartridge device with bypass channel for reducing fluid sample drift 雅培医护站股份有限公司 2023-08-11 CN disclosed
US-11352372-B2 Benzimidamides compounds comprising an oxaborinin ring INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2022-06-07 US disclosed
EP-3198272-B1 CARTRIDGE DEVICE IDENTIFICATION FOR COAGULATION ASSAYS IN FLUID SAMPLES ABBOTT POINT OF CARE INC (US) 2022-04-06 EP disclosed
EP-3955003-A1 SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES Abbott Point Of Care Inc (US) 2022-02-16 EP disclosed
EP-3954457-A2 MICROFABRICATED DEVICE WITH MICRO-ENVIRONMENT SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES Abbott Point Of Care Inc (US) 2022-02-16 EP disclosed
EP-2451467-A1 RECOMBINANT PROBIOTIC BACTERIA FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY BOWEL DISEASE (IBD) AND IRRITABLE BOWEL SYNDROME (IBS) INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2012-05-16 EP disclosed
WO-2011086172-A1 RECOMBINANT PROBIOTIC BACTERIA FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY BOWEL DISEASE (IBD) AND IRRITABLE BOWEL SYNDROME (IBS) INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2011-07-21 WO disclosed
EP-1802649-B1 SOLID PHASE PEPTIDE SYTHESIS HOFFMANN LA ROCHE (CH) 2011-01-19 EP disclosed
US-7507791-B2 Solid phase peptide synthesis of tri-peptide derivatives HOFFMANN-LA ROCHE INC. (US) 2009-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352372-B2 Benzimidamides compounds comprising an oxaborinin ring KLKB1, KLK1, KLK5 DPP4 773/4885ITGB3 2212/4885ITGA2B 2400/4885
US-11767333-B2 Benzimidamides compounds comprising an oxaborinin ring KLKB1, KLK1, KLK2 DPP4 790/4885ITGB3 2254/4885ITGA2B 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.