SCHEMBL15524993

SCHEMBL15524993

N=C(N)NCCC[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.41
NTMT1 Q9BV86 2/20 0.40
GRB2 P62993 1/20 0.39
F2 P00734 4/20 0.39
PLG P00747 1/20 0.37
OPRM1 P35372 2/20 0.37
OPRK1 P41145 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7853147 1.00 DPP4 (0.41) DPP4NTMT1GRB2F2PLG
SCHEMBL9577364 1.00 DPP4 (0.41) DPP4NTMT1GRB2F2PLG
SCHEMBL31124688 0.96 OPRM1 (0.41) NTMT1GRB2F2OPRM1OPRK1
SCHEMBL31437198 0.93 NTMT1 (0.41) DPP4NTMT1F2OPRM1OPRK1
SCHEMBL29569634 0.92 NTMT1 (0.47) NTMT1GRB2F2OPRM1OPRK1
SCHEMBL29886815 0.91 DPP4 (0.42) DPP4NTMT1GRB2F2PLG
SCHEMBL30452201 0.91 NRP1 (0.43) GRB2OPRM1OPRK1
SCHEMBL29556306 0.91 BDKRB2 (0.39) DPP4OPRM1
SCHEMBL5863304 0.91 EPHA2 (0.41) DPP4NTMT1OPRM1OPRK1
SCHEMBL31124690 0.91 OPRM1 (0.43) OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11613743-B2 Process for the production and purification of the collagenase enzyme from Vibrio alginolyticus FIDIA FARMACEUTICI S.P.A. (IT) 2023-03-28 US disclosed
US-20200354707-A1 PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS FIDIA FARMACEUTICI S.P.A. (IT) 2020-11-12 US disclosed
US-10774319-B2 Process for the production and purification of the collagenase enzyme from vibrio alginolyticus FIDIA FARMACEUTICI S.P.A. (IT) 2020-09-15 US disclosed
CN-111424025-A Novel method for producing and purifying collagenase from Vibrio alginolyticus (Vibrio algirlyticus) 菲迪亚制药股份公司 2020-07-17 CN disclosed
CN-104508127-B Novel method for producing and purifying collagenase from Vibrio alginolyticus (Vibrio algirlyticus) 菲迪亚制药股份公司 2020-04-10 CN disclosed
US-20170314005-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS FIDIA FARMACEUTICI S.P.A. (IT) 2017-11-02 US disclosed
US-9738883-B2 Process for the production and purification of the collagenase enzyme from vibrio alginolyticus FIDIA FARMACEUTICALS S.P.A. (IT) 2017-08-22 US disclosed
EP-2839000-B1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS FIDIA FARMACEUTICI (IT) 2016-04-13 EP disclosed
US-20150056179-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS FIDIA FARMACEUTICI S.P.A. (IT) 2015-02-26 US disclosed
EP-2839000-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS Fidia Farmaceutici S.p.A. (IT) 2015-02-25 EP disclosed
WO-2013156525-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS FIDIA FARMACEUTICI S.P.A. (IT) 2013-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150056179-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS MMP8, MMP1, MMP2 DPP4 555/4885NTMT1 2466/4885GRB2 4765/4885
US-10774319-B2 Process for the production and purification of the collagenase enzyme from vibrio alginolyticus MMP8, MMP1, MMP2 DPP4 567/4885NTMT1 2635/4885GRB2 4740/4885
US-20170314005-A1 NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF THE COLLAGENASE ENZYME FROM VIBRIO ALGINOLYTICUS MMP8, MMP1, MMP2 DPP4 519/4885NTMT1 2550/4885GRB2 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.