SCHEMBL1921152

SCHEMBL1921152

Cc1cc(C)cc(Nc2ccc(-c3ccc(Nc4cc(C)cc(C)c4)cc3)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.50
L3MBTL1 Q9Y468 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
GAA P10253 4/20 0.48
G6PD P11413 1/20 0.48
NPSR1 Q6W5P4 2/20 0.46
HPGD P15428 2/20 0.46
MAPT P10636 5/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 2/20 0.41
THRB P10828 2/20 0.41
LMNA P02545 2/20 0.41
GLA P06280 1/20 0.41
RCE1 Q9Y256 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
RXRA P19793 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921445 0.92 RAPGEF4 (0.56) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL12249869 0.91 HPGD (0.56) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL5604520 0.87 GAA (0.61) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL1323030 0.84 RAPGEF4 (0.65) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL19660629 0.82 MEN1 (0.52) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL21128590 0.82 RAPGEF4 (0.39) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL1921510 0.81 HPGD (0.67) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL5918700 0.81 HPGD (0.67) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL15178042 0.81 HPGD (0.67) RAPGEF4L3MBTL1MEN1KMT2AGAA
SCHEMBL3654559 0.81 ALDH1A1 (0.54) RAPGEF4L3MBTL1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed