SCHEMBL1921445

SCHEMBL1921445

Cc1cc(C)cc(Nc2ccc(Nc3cc(C)cc(C)c3)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.56
L3MBTL1 Q9Y468 5/20 0.54
GAA P10253 4/20 0.54
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
G6PD P11413 1/20 0.54
HPGD P15428 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
MAPT P10636 6/20 0.44
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
THRB P10828 2/20 0.44
GLA P06280 1/20 0.44
RCE1 Q9Y256 1/20 0.44
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX12 P18054 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604520 0.95 GAA (0.61) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL1921152 0.92 RAPGEF4 (0.50) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL1323030 0.91 RAPGEF4 (0.65) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL20564715 0.88 MEN1 (0.47) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL3654559 0.88 ALDH1A1 (0.54) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL1688844 0.87 NPSR1 (0.71) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL12249869 0.84 HPGD (0.56) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL5175021 0.84 NFKB1 (0.47) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL28792759 0.84 TSHR (0.50) RAPGEF4L3MBTL1GAAMEN1KMT2A
SCHEMBL13983094 0.84 MAPT (0.71) L3MBTL1GAAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed