Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515742 | 0.88 | CHRM2 (0.55) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL825189 | 0.86 | SMN1; SMN2 (0.68) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL4404505 | 0.86 | CHRM2 (0.53) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL23481363 | 0.85 | MAPT (0.54) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL5562538 | 0.85 | SMN1; SMN2 (0.81) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL28241166 | 0.84 | MEN1 (0.61) | TDP1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL4409089 | 0.84 | CHRM2 (0.57) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL14293611 | 0.81 | CHRM2 (0.48) | TDP1MAPTSMN1; SMN2LIN28ACHRM2 | |
| SCHEMBL5590271 | 0.81 | MAPT (0.68) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL29670844 | 0.81 | MAPT (0.68) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955363-A | Ligand recovery method based on water-soluble copper complex | 常熟理工学院 | 2024-11-15 | — | — | CN | disclosed |
| US-11904307-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-02-20 | — | — | US | disclosed |
| EP-3414275-B1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | UNIV RAMOT (IL) | 2023-07-05 | — | — | EP | disclosed |
| US-20220395820-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-12-15 | — | — | US | disclosed |
| US-11452998-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-09-27 | — | — | US | disclosed |
| US-20190039058-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-02-07 | — | — | US | disclosed |
| EP-3414275-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | Ramot at Tel-Aviv University Ltd. (IL) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137990-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395820-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | NCLN, NCL, LGMN | TDP1 3794/4885MAPT 3240/4885SMN1; SMN2 3967/4885 |
| US-11904307-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | NCLN, NCL, LGMN | TDP1 3794/4885MAPT 3240/4885SMN1; SMN2 3967/4885 |
| US-11452998-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | NCLN, NCL, LGMN | TDP1 3794/4885MAPT 3240/4885SMN1; SMN2 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.