SCHEMBL19212003

SCHEMBL19212003

CCC(C(CP(=O)(O)O)CP(=O)(O)O)P(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.42
FDPS P14324 8/20 0.37
METAP1 P53582 2/20 0.37
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP8 P22894 1/20 0.32
CA9 Q16790 1/20 0.32
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10976991 0.75 GABBR2 (0.52) LAP3METAP1GABBR2GABBR1MMP2
SCHEMBL26310679 0.75 LAP3 (0.42) LAP3FDPSMETAP1GABBR2GABBR1
SCHEMBL19212007 0.74 LAP3 (0.46) LAP3FDPSMETAP1CA12CA1
SCHEMBL8015730 0.74 LAP3 (0.46) LAP3FDPSMETAP1MMP1MMP2
SCHEMBL16797954 0.72 LAP3 (0.44) LAP3FDPSMETAP1MMP1MMP2
SCHEMBL28539152 0.72 LAP3 (0.44) LAP3FDPSMETAP1MMP1MMP2
SCHEMBL2787540 0.72 GABBR2 (0.46) GABBR2GABBR1MMP2FOLH1
SCHEMBL7961190 0.70 LAP3 (0.48) LAP3FDPSMETAP1GABBR2GABBR1
SCHEMBL2850492 0.70 LAP3 (0.54) LAP3FDPSMETAP1
SCHEMBL30585641 0.70 LAP3 (0.42) LAP3FDPSMETAP1GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
EP-3413934-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS Nano Bridging Molecules SA (CH) 2018-12-19 EP claimed
WO-2017137623-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2017-08-17 WO claimed
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP disclosed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN disclosed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US disclosed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US disclosed
EP-3413934-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS Nano Bridging Molecules SA (CH) 2018-12-19 EP disclosed
WO-2017137623-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2017-08-17 WO disclosed