Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 8/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212081 | 0.82 | LAP3 (0.41) | LAP3FDPSMETAP1MMP2MMP1 | |
| SCHEMBL8015730 | 0.78 | LAP3 (0.46) | LAP3FDPSMETAP1MMP2MMP1 | |
| SCHEMBL19212095 | 0.77 | KDM4E (0.37) | LAP3FDPSMMP2CA2KDM4E | |
| SCHEMBL28539152 | 0.76 | LAP3 (0.44) | LAP3FDPSMETAP1MMP2MMP1 | |
| SCHEMBL16797954 | 0.76 | LAP3 (0.44) | LAP3FDPSMETAP1MMP2MMP1 | |
| SCHEMBL250731 | 0.74 | GABBR2 (0.40) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| SCHEMBL6227459 | 0.74 | LAP3 (0.54) | LAP3FDPSMETAP1ALDH1A1 | |
| SCHEMBL2850492 | 0.74 | LAP3 (0.54) | LAP3FDPSMETAP1ALDH1A1 | |
| SCHEMBL30585641 | 0.74 | LAP3 (0.42) | LAP3FDPSMETAP1MMP2MMP1 | |
| SCHEMBL19212003 | 0.74 | LAP3 (0.42) | LAP3FDPSMETAP1MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413934-B1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2021-10-13 | — | — | EP | claimed |
| CN-109195641-B | Improved implant treatment with phosphonic acid compounds | 纳米桥接分子股份公司 | 2021-07-27 | — | — | CN | claimed |
| US-11000627-B2 | Treatment of implants with phosphonic acid compounds | NANO BRIDGING MOLECULES SA (CH) | 2021-05-11 | — | — | US | claimed |
| US-20190038802-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2019-02-07 | — | — | US | claimed |
| EP-3413934-B1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2021-10-13 | — | — | EP | disclosed |
| CN-109195641-B | Improved implant treatment with phosphonic acid compounds | 纳米桥接分子股份公司 | 2021-07-27 | — | — | CN | disclosed |
| US-11000627-B2 | Treatment of implants with phosphonic acid compounds | NANO BRIDGING MOLECULES SA (CH) | 2021-05-11 | — | — | US | disclosed |
| US-20190038802-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2019-02-07 | — | — | US | disclosed |
| EP-3413934-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | Nano Bridging Molecules SA (CH) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137623-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2017-08-17 | — | — | WO | disclosed |