SCHEMBL19212010

SCHEMBL19212010

O=[PH](O)OP(=O)(O)C1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
FDPS P14324 1/20 0.31
MMP8 P22894 1/20 0.31
MMP1 P03956 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19212098 0.98
SCHEMBL9738090 0.89
SCHEMBL17488891 0.75 MMP2 (0.37) MMP2CA12CA1CA2CA9
SCHEMBL29467371 0.71 FDPS (0.41) MMP2CA12CA1CA2CA9
SCHEMBL29796765 0.71 FDPS (0.41) MMP2CA12CA1CA2CA9
SCHEMBL27792299 0.71 MMP2 (0.37) MMP2CA12CA1CA2CA9
SCHEMBL15792481 0.71 MMP2 (0.35) MMP2CA12CA1CA2CA9
Methane SCHEMBL11749189 0.70 FDPS (0.39) MMP2CA12CA1CA2CA9
SCHEMBL27936234 0.70 MMP2 (0.33) MMP2CA12CA1CA2CA9
SCHEMBL3827313 0.70 ACHE (0.45) MMP2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
EP-3413934-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS Nano Bridging Molecules SA (CH) 2018-12-19 EP disclosed
WO-2017137623-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2017-08-17 WO disclosed