Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820043 | 0.76 | HAVCR2 (1.00) | HAVCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL19583298 | 0.74 | CUL4A (0.50) | HAVCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4888217 | 0.72 | ALDH1A1 (0.66) | HAVCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5233820 | 0.70 | HAVCR2 (0.62) | HAVCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL26566413 | 0.64 | RECQL (0.33) | RECQL | |
| SCHEMBL13277489 | 0.63 | KDM4E (0.54) | HAVCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL20339837 | 0.62 | KDM4E (0.57) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL4196229 | 0.62 | KDM4E (0.38) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL15691382 | 0.61 | NTRK1 (0.35) | ALDH1A1KDM4EMAPTGAARECQL | |
| SCHEMBL13058619 | 0.59 | GABRA1 (0.40) | ALDH1A1HPGDKDM4EMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913753-B2 | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | VALO EARLY DISCOVERY, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3414252-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139778-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913753-B2 | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | HAVCR2 3674/4885ALDH1A1 2323/4885HPGD 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.