SCHEMBL19212286

SCHEMBL19212286

O=C(OCc1[c]cccc1)C1CC1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.40
RAB9A P51151 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
NPC1 O15118 3/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
LMNA P02545 1/20 0.39
PKM P14618 1/20 0.39
ALDH1A1 P00352 2/20 0.39
FABP7 O15540 1/20 0.38
FABP5 Q01469 1/20 0.38
ATM Q13315 1/20 0.38
POLB P06746 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ELANE P08246 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22635945 0.77 ALDH1A1 (0.39) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
SCHEMBL9401129 0.76 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1MAPTLMNAPKM
SCHEMBL22400 0.76 ALDH1A1 (0.53) SMN1; SMN2L3MBTL1MAPTLMNAALDH1A1
SCHEMBL10917021 0.74 FABP7 (0.58) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
SCHEMBL280126 0.74 FABP7 (0.58) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
SCHEMBL6666657 0.74 FABP7 (0.58) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
SCHEMBL25743 0.73 TDP1 (0.58) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
SCHEMBL7847914 0.73 LTA4H (0.56) SMN1; SMN2L3MBTL1MAPTLMNAALDH1A1
Hydrochloric Acid SCHEMBL27944947 0.73 FABP7 (0.57) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1
Hydrochloric Acid SCHEMBL27765522 0.73 FABP7 (0.57) HPGDRAB9ASMN1; SMN2L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3414236-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2018-12-19 EP disclosed
WO-2017137338-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 WO disclosed