SCHEMBL1921241

SCHEMBL1921241

CC=C[C@@H]1[C@@H](C(=O)OCc2c(F)c(F)c(COC)c(F)c2F)C1(C)C

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ADRA2A P08913 1/20 0.34
CNR1 P21554 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134831 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1921242 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1921239 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL117637 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL7592007 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29268645 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL24119147 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL21959829 0.94 TDP1 (0.58) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29911393 0.94 TDP1 (0.49) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29843131 0.94 TDP1 (0.49) TDP1MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060052444-A1 Arthropod controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED 2006-03-09 US claimed
CN-118401494-B Cyclopropane carboxylic acid ester compound and use thereof 住友化学株式会社 2025-02-25 CN disclosed
CN-118339135-B Ester compound and use thereof 住友化学株式会社 2025-01-07 CN disclosed
CN-118339137-B Ester compound and use thereof 住友化学株式会社 2024-12-20 CN disclosed
CN-118401494-A Cyclopropane carboxylic acid ester compound and use thereof 住友化学株式会社 2024-07-26 CN disclosed
CN-118339137-A Ester compound and use thereof 住友化学株式会社 2024-07-12 CN disclosed
CN-118339135-A Ester compound and use thereof 住友化学株式会社 2024-07-12 CN disclosed
WO-2024071447-A2 ESTER COMPOUND AND USE THEREOF 住友化学株式会社 2024-04-04 WO disclosed
WO-2024071443-A2 ESTER COMPOUND AND USE THEREOF 住友化学株式会社 2024-04-04 WO disclosed
WO-2024071444-A2 CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND AND USE THEREOF 住友化学株式会社 2024-04-04 WO disclosed
EP-2034840-B1 PESTICIDAL COMPOSITION COMPRISING TETRAFLUOROBENZYL CYCLOPROPANE CARBOXYLATES SUMITOMO CHEMICAL CO (JP) 2011-06-01 EP disclosed
US-20090326064-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-31 US disclosed
EP-1625792-B1 Pesticidal composition SUMITOMO CHEMICAL CO (JP) 2007-06-06 EP disclosed
US-20060052444-A1 Arthropod controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED 2006-03-09 US disclosed
US-20060035947-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-16 US disclosed
EP-1625792-A1 Pesticidal composition Sumitomo Chemical Company, Limited (JP) 2006-02-15 EP disclosed
US-6706910-B2 BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-16 US disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060035947-A1 Pesticidal composition ACHE, PRMT7, DDT TDP1 2816/4885MEN1 729/4885KMT2A 505/4885
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 TDP1 4384/4885MEN1 2199/4885KMT2A 2204/4885
US-20060052444-A1 Arthropod controlling agent RRP12, NOP2, YTHDF1 TDP1 3372/4885MEN1 1035/4885KMT2A 35/4885
US-20090326064-A1 Pesticidal composition PRMT1, DDT, CARM1 TDP1 3827/4885MEN1 551/4885KMT2A 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.