Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18111366 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL28200465 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAMGLLMAPTKMT2A | |
| SCHEMBL19212417 | 0.78 | BACE1 (0.38) | ALDH1A1IDO1KDM4E | |
| SCHEMBL18111841 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL11448379 | 0.77 | HCAR3 (0.49) | ALDH1A1LMNAHTTRAB9ANPC1 | |
| SCHEMBL19212394 | 0.76 | IDO1 (0.59) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL30783381 | 0.75 | ALDH1A1 (0.39) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL19243417 | 0.75 | ALDH1A1 (0.39) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL18112153 | 0.74 | IDO1 (0.40) | ALDH1A1ALDH3A1LMNAHTTRAB9A | |
| SCHEMBL18112230 | 0.74 | IDO1 (0.40) | ALDH1A1ALDH3A1LMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414224-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | Inventisbio Inc. (KY) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139414-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO INC. (KY) | 2017-08-17 | — | — | WO | disclosed |