Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20321883 | 0.85 | IDO1 (0.39) | ALDH1A1KMT2AMCOLN3MEN1KDM4E | |
| SCHEMBL28200454 | 0.83 | KDM4E (0.38) | ALDH1A1KMT2AMCOLN3MEN1KDM4E | |
| SCHEMBL18111366 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL28328527 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EACHE | |
| SCHEMBL19212438 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL11448379 | 0.80 | HCAR3 (0.49) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL30936695 | 0.79 | LMNA (0.49) | ALDH1A1KMT2AMCOLN3MEN1KDM4E | |
| SCHEMBL8859336 | 0.76 | KMT2A (0.46) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL10473352 | 0.75 | LMNA (0.51) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL18111841 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108093636-A | Indoleamine 2, 3-dioxygenase inhibitors for the treatment of cancer | 百时美施贵宝公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-107743481-A | Indoleamine 2, 3-dioxygenase inhibitors for the treatment of cancer | 百时美施贵宝公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-107743490-A | For the indoleamine 2 for the treatment of cancer, 3 dioxygenase inhibitors | 百时美施贵宝公司 | 2018-02-27 | — | — | CN | disclosed |