Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921399 | 0.94 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL14321912 | 0.89 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7467173 | 0.87 | THRB (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL233287 | 0.86 | POLB (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1562514 | 0.86 | POLB (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL232155 | 0.86 | POLB (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL342384 | 0.86 | POLB (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL4447342 | 0.86 | POLB (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL146245 | 0.84 | POLB (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL20847831 | 0.84 | HRH1 (0.43) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658735-B2 | Polymerizable monomer, graft copolymer, and surface modifier | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20110269905-A1 | Polymerizable Monomer, Graft Copolymer, and Surface Modifier | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2011-11-03 | — | — | US | disclosed |
| EP-2330138-A1 | POLYMERIZABLE MONOMER, GRAFT COPOLYMER, AND SURFACE MODIFIER | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2011-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269905-A1 | Polymerizable Monomer, Graft Copolymer, and Surface Modifier | ITGA1, CHRM1, C3AR1 | TSHR 1593/4885POLB 4264/4885APEX1 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.