Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857687 | 0.80 | MET (0.53) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL9125664 | 0.80 | MET (0.53) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL26540055 | 0.80 | MET (0.47) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL67670 | 0.80 | MET (0.49) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL10644450 | 0.79 | MCHR1 (0.54) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL9965980 | 0.78 | GRM5 (0.50) | MEN1POLBKMT2AMCHR1GRM5 | |
| SCHEMBL9963327 | 0.78 | MEN1 (0.47) | MEN1POLBKMT2ATLR8MCHR1 | |
| SCHEMBL29015868 | 0.77 | MET (0.47) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL10643589 | 0.77 | LTA4H (0.54) | METLTA4HMAPK14NOS3NOS1 | |
| SCHEMBL26701297 | 0.77 | MET (0.47) | METLTA4HMAPK14NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929708-B | 4- [ [ (7-Aminopyrazolo [1,5-a ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds and their therapeutic uses | 卡里克治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. | 2023-03-23 | — | — | US | disclosed |
| CN-104159891-B | Pyridazine amide compound and they are as the purposes of SYK inhibitor | 霍夫曼-拉罗奇有限公司 | 2016-09-07 | — | — | CN | disclosed |
| US-20110160227-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC | 2011-06-30 | — | — | US | disclosed |
| EP-2326178-A2 | PROLYL HYDROXYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010022307-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |
| US-5459132-A | Inhibition of cell proliferation, analgesic, hypotensive | LABORATOIRES UPSA (FR) | 1995-10-17 | — | — | US | disclosed |
| WO-1995018817-A1 | NOVEL ADENOSINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1995-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160227-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN2, EGLN3 | MET 580/4885LTA4H 1596/4885MAPK14 3479/4885 |
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | IRAK4, IRAK2, IRAK1 | MET 1618/4885LTA4H 980/4885MAPK14 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.