Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473713 | 0.89 | MCHR1 (0.44) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL1921437 | 0.79 | MET (0.52) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL11838849 | 0.77 | MCHR1 (0.54) | MCHR1SMN1; SMN2SLC6A2MEN1KMT2A | |
| SCHEMBL1341433 | 0.76 | MCHR1 (0.55) | MCHR1MAPTCDK8CDK5ROCK1 | |
| SCHEMBL26701301 | 0.75 | MET (0.47) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL1921438 | 0.74 | LTA4H (0.56) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL1002382 | 0.73 | LTA4H (0.59) | LTA4HMAPK14NPC1RAB9AHTT | |
| SCHEMBL10643589 | 0.73 | LTA4H (0.54) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL7222828 | 0.73 | CYP1A2 (0.59) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL29015868 | 0.73 | MET (0.47) | METLTA4HMAPK14NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87106804-A | Imidazopyridine derivatives, the pharmaceutical compositions that contains imidazopyridine derivatives and their preparation method | — | 1988-05-18 | — | — | CN | disclosed |
| EP-0266890-A1 | Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |