Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934328 | 0.83 | METAP2 (0.40) | ALDH1A1LMNACHRM1HSD17B10 | |
| SCHEMBL7033401 | 0.83 | CYP1A2 (0.36) | HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31065465 | 0.80 | ALDH1A1 (0.48) | HCAR2ALDH1A1LMNAESR1TSHR | |
| SCHEMBL12555764 | 0.79 | SMN1; SMN2 (0.37) | ALDH1A1HSD17B10 | |
| SCHEMBL18560257 | 0.79 | MGAM (0.35) | — | |
| SCHEMBL9792994 | 0.78 | MME (0.39) | ALDH1A1 | |
| SCHEMBL11655381 | 0.77 | NAAA (0.50) | HCAR2ALDH1A1LMNATSHR | |
| SCHEMBL6735471 | 0.77 | HCAR2 (0.38) | HCAR2ALDH1A1LMNAHDAC3HDAC4 | |
| SCHEMBL805664 | 0.76 | HCAR2 (0.40) | HCAR2ALDH1A1LMNAHDAC3HDAC4 | |
| SCHEMBL17617139 | 0.76 | HCAR2 (0.40) | HCAR2ALDH1A1LMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226499-A1 | PROTEIN-STABILIZING AGENT AND PROTEIN-STABILIZING METHOD | NOF CORPORATION (JP) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226499-A1 | PROTEIN-STABILIZING AGENT AND PROTEIN-STABILIZING METHOD | MRPL21, SERBP1, IK | HCAR2 4797/4885ALDH1A1 1898/4885LMNA 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.