SCHEMBL1921452

SCHEMBL1921452

FC(F)(F)c1ccc(Nc2ccc(-c3ccc(Nc4ccc(C(F)(F)F)cc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 13/20 0.68
EPHX2 P34913 2/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
AKR1C3 P42330 1/20 0.46
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394422 0.92 EPHX2 (0.56) KIF11EPHX2CA1CA2
SCHEMBL1921455 0.92 EPHX2 (0.56) KIF11EPHX2CA1CA2
SCHEMBL29914837 0.84 KIF11 (0.78) KIF11CA1CA2
SCHEMBL197238 0.84 KIF11 (0.78) KIF11CA1CA2
SCHEMBL13410633 0.84 KIF11 (0.78) KIF11CA1CA2
SCHEMBL16481461 0.83 MAOB (0.49) KIF11EPHX2CA1CA2
SCHEMBL503225 0.83 ALDH1A1 (0.62) KIF11EPHX2
SCHEMBL23059923 0.81 AKR1C3 (0.50) KIF11EPHX2CA1CA2AKR1C3
SCHEMBL2705763 0.81 EPHX2 (0.47) KIF11EPHX2CA1CA2
SCHEMBL2131497 0.81 KIF11 (0.64) KIF11EPHX2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed