SCHEMBL197238

SCHEMBL197238

FC(F)(F)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 14/20 0.78
MAOB P27338 1/20 0.56
ALDH1A1 P00352 1/20 0.56
TSHR P16473 1/20 0.56
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
ORAI1 Q96D31 1/20 0.50
ORAI2 Q96SN7 1/20 0.50
ORAI3 Q9BRQ5 1/20 0.50
TRPV6 Q9H1D0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13410633 1.00 KIF11 (0.78) KIF11MAOBALDH1A1TSHRCA1
SCHEMBL29914837 1.00 KIF11 (0.78) KIF11MAOBALDH1A1TSHRCA1
SCHEMBL12937177 0.91 KIF11 (0.67) KIF11MAOBALDH1A1TSHRCA1
SCHEMBL63468 0.89 ALDH1A1 (0.67) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL7940597 0.88 KIF11 (0.64) KIF11MAOBALDH1A1TSHRCA1
SCHEMBL163728 0.88 KIF11 (1.00) KIF11ALDH1A1TSHRTRPV6
SCHEMBL1044865 0.86 KIF11 (0.61) KIF11MAOBALDH1A1TSHRCA1
SCHEMBL13410613 0.86 KIF11 (1.00) KIF11MAOB
Ammonia Solution, Strong SCHEMBL21809401 0.86 KIF11 (0.95) KIF11ALDH1A1TSHRTRPV6
SCHEMBL12675678 0.86 KIF11 (1.00) KIF11ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108822317-B Preparation method of graphene polyimide heating film 杭州牛墨科技有限公司 2021-04-06 CN claimed
US-12392042-B2 Alternating current (AC) transition-metal catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-08-19 US disclosed
US-20250033002-A1 Porous Polybenzimidazole Membrane Supports for Composite Membranes U.S. DEPARTMENT OF ENERGY 2025-01-30 US disclosed
US-12138599-B2 Porous polybenzimidazole membrane supports for composite membranes BATTELLE MEMORIAL INSTITUTE (US) 2024-11-12 US disclosed
CN-114605300-B Synthesis method of aryl selenocyanate compound 浙江工业大学 2024-03-26 CN disclosed
US-20230407492-A1 ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-12-21 US disclosed
CN-114149298-B Method for preparing biaryl compound from arylboronic acid by hydrazone catalyst 江西麦豪化工科技有限公司 2023-11-24 CN disclosed
CN-117075426-A Curable resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2023-11-17 CN disclosed
US-11767473-B2 Active nematic colloids in microrobotics THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-09-26 US disclosed
CN-111886293-B Curable resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2023-08-01 CN disclosed
US-7193100-B2 Haloaluminoxane compositions, their preparation, and their use in catalysis ALBEMARLE CORPORATION (US) 2007-03-20 US disclosed
WO-2007005364-A2 HALOALUMINOXANE COMPOSITIONS ALBEMARLE CORPORATION (US) 2007-01-11 WO disclosed
US-20060287448-A1 Haloaluminoxane compositions, their preparation, and their use in catalysis W. R. GRACE & CO-CONN. 2006-12-21 US disclosed
EP-1701963-A1 HALOALUMINOXANE COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS ALBEMARLE CORPORATION (US) 2006-09-20 EP disclosed
WO-2005066191-A1 HALOALUMINOXANE COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS ALBEMARLE CORPORATION (US) 2005-07-21 WO disclosed
US-20050143254-A1 Haloaluminoxane compositions, their preparation, and their use in catalysis W. R. GRACE & CO.-CONN. 2005-06-30 US disclosed
US-20010034459-A1 Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates MEUDT ANDREAS (DE) 2001-10-25 US disclosed
EP-1112991-A2 Process for the preparation of 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethylbiphenyl-2-carboxylic acid from o-tolylmetallates Clariant GmbH (DE) 2001-07-04 EP disclosed
EP-0446301-A1 PREPARATION OF BIARYL COMPOUNDS. EASTMAN KODAK CO (US) 1991-09-18 EP disclosed
WO-1990006295-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1990-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034459-A1 Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates ZC3HAV1L, ZRANB2, ZFP3 KIF11 707/4885MAOB 171/4885ALDH1A1 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.