SCHEMBL1921463

SCHEMBL1921463

CCC1(CC)c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.50
PGR P06401 4/20 0.49
AKR1A1 P14550 2/20 0.45
AKR1B1 P15121 2/20 0.45
S100A4 P26447 1/20 0.39
GPR3 P46089 1/20 0.38
APEX1 P27695 1/20 0.36
MDM2 Q00987 1/20 0.35
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921866 0.91 PDK2 (0.47) PDK2PGRAKR1A1AKR1B1S100A4
SCHEMBL1921910 0.83 PDK2 (0.45) PDK2PGRAKR1A1AKR1B1S100A4
SCHEMBL1271141 0.83 APEX1 (0.41) PDK2PGRAPEX1ELANE
SCHEMBL29484836 0.82 APEX1 (0.47) PDK2PGRS100A4APEX1ELANE
SCHEMBL1394829 0.82 APEX1 (0.47) PDK2PGRS100A4APEX1ELANE
SCHEMBL2129264 0.81 PDK2 (0.44) PDK2
SCHEMBL1920734 0.81 PDK2 (0.43) PDK2PGRAKR1A1AKR1B1GPR3
SCHEMBL1921634 0.81 PDK2 (0.43) PDK2PGRAKR1A1AKR1B1GPR3
SCHEMBL20542581 0.81 PDK2 (0.40) PDK2PGRAKR1A1AKR1B1MDM2
SCHEMBL660283 0.79 PDK2 (0.36) PDK2PGRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed