SCHEMBL1921469

SCHEMBL1921469

Cc1ccc(C)c(Nc2ccc(-c3ccc(Nc4cc(C)ccc4C)cc3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.57
GAA P10253 7/20 0.44
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
G6PD P11413 1/20 0.42
EGFR P00533 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPKAPK2 P49137 1/20 0.41
GALR2 O43603 1/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HSD17B10 Q99714 2/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921826 0.94 RAPGEF4 (0.63) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL22814295 0.93 RAPGEF4 (0.50) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL17858219 0.91 RAPGEF4 (0.61) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL8691617 0.83 RAPGEF4 (0.57) RAPGEF4GAAMEN1KMT2AHTT
SCHEMBL1921480 0.83 RAPGEF4 (0.59) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL29196035 0.82 RAPGEF4 (0.71) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL15478852 0.82 RAPGEF4 (0.57) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL3634234 0.81 GAA (0.55) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL22814248 0.81 ALDH1A1 (0.60) RAPGEF4GAAALDH1A1MEN1KMT2A
SCHEMBL17858154 0.81 RAPGEF4 (0.50) RAPGEF4GAAALDH1A1L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed