SCHEMBL19214780

SCHEMBL19214780

Nc1cccc(CNCc2ccccn2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.54
MAOB P27338 3/20 0.54
CHRM2 P08172 1/20 0.53
KDM4E B2RXH2 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SIRT2 Q8IXJ6 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
SCN8A Q9UQD0 1/20 0.46
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45
NOS2 P35228 1/20 0.45
PI4KA P42356 1/20 0.45
PI4K2B Q8TCG2 1/20 0.45
PI4K2A Q9BTU6 1/20 0.45
PI4KB Q9UBF8 1/20 0.45
PRMT1 Q99873 1/20 0.44
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9777455 0.87 CHRM2 (0.61) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL18465500 0.87 KCNH3 (0.45) SMN1; SMN2NOS3NOS1NOS2
SCHEMBL29438821 0.83 CHRM2 (0.70) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL230222 0.83 CHRM2 (0.70) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL25211342 0.81 CHRM2 (0.68) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL18493706 0.81 CHRM2 (0.68) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL317984 0.81 CHRM2 (0.68) MAOAMAOBCHRM2KDM4EL3MBTL1
Zinc Ion SCHEMBL30442739 0.81 CHRM2 (0.68) MAOAMAOBCHRM2KDM4EL3MBTL1
Zinc Ion SCHEMBL30205248 0.81 CHRM2 (0.68) MAOAMAOBCHRM2KDM4EL3MBTL1
SCHEMBL18160890 0.81 CHRM2 (0.54) MAOAMAOBCHRM2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 MAOA 2578/4885MAOB 3497/4885CHRM2 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.