Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452452 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16547521 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8817477 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8817832 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8817532 | 0.89 | PPM1B (0.43) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7858102 | 0.84 | ALDH1A1 (0.54) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7858097 | 0.84 | ALDH1A1 (0.54) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7858104 | 0.84 | ALDH1A1 (0.54) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6128867 | 0.83 | MEN1 (0.43) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14034644 | 0.83 | MEN1 (0.43) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | JANSSEN SCIENCES IRELAND UC (IE) | 2020-03-24 | — | — | US | disclosed |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN INFECTIOUS DISEASES BVBA (BE) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | IDO1, IDO2, INMT | MEN1 2223/4885ALDH1A1 143/4885CYP1A2 20/4885 |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | IDO1, IDO2, INMT | MEN1 2223/4885ALDH1A1 143/4885CYP1A2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.