Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488542 | 0.95 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL5583848 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL14284346 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL22722011 | 0.83 | ELANE (0.49) | ALDH1A1KDM4EGAARAB9ACNR2 | |
| SCHEMBL12436726 | 0.83 | ELANE (0.49) | ALDH1A1KDM4EGAARAB9ACNR2 | |
| SCHEMBL22449359 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL9207305 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL9207132 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAARAB9AKMT2A | |
| SCHEMBL20068957 | 0.79 | KDM5A (0.57) | ALDH1A1KDM5A | |
| SCHEMBL31432000 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | JANSSEN SCIENCES IRELAND UC (IE) | 2020-03-24 | — | — | US | disclosed |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN INFECTIOUS DISEASES BVBA (BE) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | IDO1, IDO2, INMT | ALDH1A1 143/4885KDM4E 545/4885GAA 3541/4885 |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | IDO1, IDO2, INMT | ALDH1A1 143/4885KDM4E 545/4885GAA 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.