SCHEMBL5583848

SCHEMBL5583848

O=C(NC1CCCCC1)c1ncccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.66
KDM4E B2RXH2 2/20 0.66
GAA P10253 1/20 0.66
RAB9A P51151 4/20 0.59
NPC1 O15118 4/20 0.59
LMNA P02545 1/20 0.59
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
HIF1A Q16665 1/20 0.53
PPIA P62937 1/20 0.51
CNR2 P34972 2/20 0.50
CNR1 P21554 1/20 0.50
MAPT P10636 1/20 0.50
EGLN2 Q96KS0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14284346 1.00 ALDH1A1 (0.66) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL14159861 0.87 KDM4E (0.50) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL21490080 0.85 SMYD3 (0.51) ALDH1A1KDM4EGAAEGLN2FTO
SCHEMBL19701397 0.85 SMYD3 (0.51) ALDH1A1KDM4EGAAEGLN2FTO
SCHEMBL19215315 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL22449359 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL3720002 0.82 EGLN2 (0.50) ALDH1A1KDM4EGAAEGLN2FTO
SCHEMBL9207132 0.81 ALDH1A1 (0.69) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL9207305 0.81 ALDH1A1 (0.69) ALDH1A1KDM4EGAARAB9ANPC1
SCHEMBL23575882 0.81 SMYD3 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed