Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840650 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL15870678 | 0.83 | PKM (0.63) | ALDH1A1HPGDMAPTSMN1; SMN2HTT | |
| SCHEMBL15840689 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL15870681 | 0.80 | KMT2A (0.65) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL4367820 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL14096020 | 0.78 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15840669 | 0.78 | KMT2A (0.74) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL17266696 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL15870680 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL833844 | 0.77 | MAPT (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334863-A1 | Cdc42 INHIBITOR AND USES THEREOF | LU QUN (CN) | 2017-11-23 | — | — | US | disclosed |
| US-9725417-B2 | Cdc42 inhibitor and uses thereof | LU QUN (CN) | 2017-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334863-A1 | Cdc42 INHIBITOR AND USES THEREOF | CDC42, ARHGDIA, ARHGDIB | ALDH1A1 4562/4885HPGD 2433/4885MAPT 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.