SCHEMBL19215410

SCHEMBL19215410

Clc1cccc2c1[nH]c1c3cccc(Cl)c3[nH]c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 2/20 0.52
DYRK1A Q13627 5/20 0.50
DAO P14920 1/20 0.50
CHEK1 O14757 1/20 0.48
FLT3 P36888 1/20 0.48
PLK3 Q9H4B4 1/20 0.48
MAP2 P11137 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
PSMB8 P28062 1/20 0.45
CLK1 P49759 1/20 0.45
CDK9 P50750 1/20 0.45
CDK5 Q00535 1/20 0.45
DYRK2 Q92630 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
AHR P35869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27902384 0.80 KIF11 (0.57) CYP1A2CYP2A6DYRK1ADAOCHEK1
SCHEMBL23702740 0.80 PDE7A (0.48) CYP1A2CYP2A6DYRK1ADAOCHEK1
SCHEMBL7648211 0.77 DYRK1A (0.62) CYP1A2DYRK1AKDM4EPSMB8CDK5
SCHEMBL22092277 0.77 KIF11 (0.58) CYP1A2CYP2A6DYRK1ADAOKDM4E
SCHEMBL27885306 0.75 PNMT (0.53) CYP1A2CYP2A6DYRK1ADAOCHEK1
SCHEMBL28644822 0.75 CYP2A6 (0.52) CYP2A6DYRK1AMAP2KDM4ECLK1
SCHEMBL15202293 0.75 MEN1 (0.55) CYP1A2CYP2A6DYRK1ADAOCHEK1
SCHEMBL28865942 0.75 DYRK1A (0.43) CYP1A2CYP2A6DYRK1ADAOCHEK1
Hydrochloric Acid SCHEMBL29281105 0.75 DYRK1A (0.61) CYP1A2DYRK1AKDM4ETAAR1PSMB8
SCHEMBL12003871 0.75 DYRK1A (0.61) CYP1A2DYRK1AKDM4EPSMB8CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023038382-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-16 WO disclosed
US-10193070-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2019-01-29 US disclosed
US-20170229654-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193070-B2 Electroactive materials EPX, INA, KCNN2 CYP1A2 674/4885CYP2A6 778/4885DYRK1A 4579/4885
US-20170229654-A1 ELECTROACTIVE MATERIALS EPX, INA, KCNN2 CYP1A2 674/4885CYP2A6 778/4885DYRK1A 4579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.