Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883536 | 0.84 | ERN1 (0.67) | ERN1PIM1 | |
| SCHEMBL13190731 | 0.83 | ALOX5 (0.49) | ERN1EGFRTYRALOX5PTGS2 | |
| SCHEMBL3967922 | 0.82 | NPC1 (0.44) | ERN1EGFRTYRALOX5PTGS2 | |
| SCHEMBL22763890 | 0.81 | ERN1 (0.51) | ERN1EGFRTYRALOX5PTGS2 | |
| SCHEMBL22764010 | 0.78 | ERN1 (0.45) | ERN1TYRALOX5PTGS2 | |
| SCHEMBL15151739 | 0.78 | CYP2C19 (0.39) | ERN1EGFRTYRMAOAALOX5 | |
| SCHEMBL8393034 | 0.78 | TYR (0.43) | EGFRTYRMAOAALOX5PTGS2 | |
| SCHEMBL5021200 | 0.78 | ERN1 (0.67) | ERN1PIM1 | |
| SCHEMBL5673519 | 0.76 | PTGS2 (0.50) | EGFRALOX5PTGS2 | |
| SCHEMBL38662732 | 0.75 | PTGS2 (0.53) | EGFRTYRALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377850-B2 | Polyester stereocomplexes, compositions comprising same, and methods of making and using same | CORNELL UNIVERSITY (US) | 2019-08-13 | — | — | US | disclosed |
| US-20170226283-A1 | POLYESTER STEREOCOMPLEXES, COMPOSITIONS COMPRISING SAME, AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377850-B2 | Polyester stereocomplexes, compositions comprising same, and methods of making and using same | EPHX2, GNE, EPHX1 | ERN1 2302/4885EGFR 1242/4885TYR 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.