Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673519 | 0.94 | PTGS2 (0.50) | CDK1PTGS2CYP3A4GPR84EGFR | |
| SCHEMBL6141791 | 0.90 | ERN1 (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL7251486 | 0.89 | PTGS2 (0.49) | CDK1PTGS2CYP3A4GPR84EGFR | |
| SCHEMBL28528307 | 0.89 | NPC1 (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL3965795 | 0.86 | ERN1 (0.42) | CDK1ERN1LMNAMAPTALOX5 | |
| SCHEMBL11954892 | 0.85 | CDK1 (0.45) | CDK1ERN1LMNAMAPT | |
| SCHEMBL13190731 | 0.85 | ALOX5 (0.49) | MAPK1PTGS2CYP3A4GPR84ERN1 | |
| SCHEMBL22763957 | 0.83 | HTT (0.49) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8432218 | 0.83 | PTGS2 (0.56) | CDK1PTGS2CYP3A4GPR84ERN1 | |
| SCHEMBL27621298 | 0.83 | PTGS2 (0.56) | CDK1PTGS2CYP3A4GPR84ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | claimed |
| CN-101514212-A | Pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound and synthetic method thereof | UNIV LIAONING (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-1200017-C | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2005-05-04 | — | — | CN | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
| CN-1388140-A | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | claimed |
| EP-3707242-B1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | UNIV KOELN (DE) | 2022-05-18 | — | — | EP | disclosed |
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | UNIVERSITÄT ZU KÖLN (DE) | 2020-10-29 | — | — | US | disclosed |
| EP-3480296-A1 | DIAMINES FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | Universität zu Köln (DE) | 2019-05-08 | — | — | EP | disclosed |
| CN-104211682-B | Pyridine compounds and their and application thereof | 沈阳药科大学 | 2017-06-06 | — | — | CN | disclosed |
| EP-1992630-B1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | TICONA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| CN-101514212-B | Synthetic method of pyridine-2''amino-2'-hydroxybenzene methanol phenylcarbinol boric acid ester compound | UNIV LIAONING | 2011-11-09 | — | — | CN | disclosed |
| US-8007976-B2 | Electrostatic image developing toner, toner kit and image forming apparatus | RICOH COMPANY. LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| WO-2003072584-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | disclosed |
| CN-1388140-A | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | disclosed |
| EP-0952997-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1998030609-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | NPC1 923/4885HPGD 886/4885MAPK1 3677/4885 |
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | ALPG, RARB, RARG | NPC1 379/4885HPGD 2886/4885MAPK1 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.