SCHEMBL1921816

SCHEMBL1921816

CCCCC1(CCCC)c2cc(Cl)ccc2-c2ccc(Cl)cc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.42
AKR1A1 P14550 2/20 0.38
AKR1B1 P15121 2/20 0.38
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR7 P34969 2/20 0.34
PPOX P50336 1/20 0.33
NOTUM Q6P988 1/20 0.33
HSD11B1 P28845 1/20 0.33
PGR P06401 2/20 0.33
CNR1 P21554 1/20 0.33
ELANE P08246 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
S100A4 P26447 1/20 0.32
NR3C1 P04150 1/20 0.32
AR P10275 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13708991 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL196478 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL196824 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL29590106 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL197162 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL29590107 0.93 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7CNR1
SCHEMBL1921910 0.92 PDK2 (0.45) PDK2AKR1A1AKR1B1HTR7PGR
SCHEMBL1920734 0.86 PDK2 (0.43) PDK2AKR1A1AKR1B1MEN1KMT2A
SCHEMBL1921634 0.86 PDK2 (0.43) PDK2AKR1A1AKR1B1MEN1KMT2A
SCHEMBL16407235 0.86 CNR1 (0.36) PDK2AKR1A1AKR1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed