SCHEMBL19218274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2742931	0.83	KDR (0.45)	CHKAPDE5AKDRFGFR1ITK
	SCHEMBL12153510	0.82	CYP1A2 (0.39)	CYP1A2CYP1A1CYP1B1KDM4EALDH1A1
	SCHEMBL13826088	0.81	CHKA (0.50)	CHKAPDE5AKDRHSD17B1HSD17B2
	SCHEMBL6724011	0.81	CHKA (0.50)	CHKAPDE5AKDRHSD17B1HSD17B2
	SCHEMBL6723434	0.81	CHKA (0.50)	CHKAPDE5AKDRHSD17B1HSD17B2
	SCHEMBL6723784	0.81	CHKA (0.50)	CHKAPDE5AKDRHSD17B1HSD17B2
	SCHEMBL12153489	0.81	ALDH1A1 (0.38)	CYP1A2KDM4EALDH1A1CYP3A4CYP2D6
	SCHEMBL12153557	0.81	ALDH1A1 (0.38)	CYP1A2KDM4EALDH1A1CYP3A4CYP2D6
	SCHEMBL12153558	0.81	ALDH1A1 (0.38)	CYP1A2KDM4EALDH1A1CYP3A4CYP2D6
	SCHEMBL6724189	0.81	CHKA (0.49)	CHKAABCG2PDE5AALDH1A1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.