Ether

Ether

SCHEMBL1921834

CCOCC.Cc1ccc(C)c(O)c1C

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TRPA1 O75762 2/20 0.34
ATM Q13315 1/20 0.34
CYP1A2 P05177 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34
RECQL P46063 2/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.33
NQO1 P15559 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407125 0.83 ALDH1A1 (0.53) ALDH1A1TRPA1ATMCYP1A2HTR1D
SCHEMBL23915 0.83 ALDH1A1 (0.53) ALDH1A1TRPA1ATMCYP1A2HTR1D
SCHEMBL15485256 0.83 ALDH1A1 (0.53) ALDH1A1TRPA1ATMCYP1A2HTR1D
Water SCHEMBL29374093 0.78 ALDH1A1 (0.48) ALDH1A1TRPA1ATMCYP1A2HTR1D
Ether SCHEMBL11100989 0.77 MAPK1 (0.40) ALDH1A1HTR1DHTR1BLMNAGAA
SCHEMBL11018429 0.75 ALDH1A1 (0.46) ALDH1A1TRPA1ATMCYP1A2HTR1D
SCHEMBL22542329 0.75 NCF1 (0.37)
Ether SCHEMBL27534235 0.74 TRPA1 (0.71) ALDH1A1TRPA1ATMTDP1HPGD
SCHEMBL4626530 0.73 ALDH1A1 (0.74) ALDH1A1TRPA1ATMCYP1A2RECQL
Ether SCHEMBL28161113 0.73 GAA (0.44) ALDH1A1TRPA1ATMCYP1A2HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055731-B1 Method of preparing a poly(arylene ether) and a poly(arylene ether) prepared thereby SABIC INNOVATIVE PLASTICS IP (NL) 2011-06-01 EP disclosed