SCHEMBL19218376

SCHEMBL19218376

c1cc(-c2cccc3c2oc2ccccc23)cc(N(c2ccc3c4ccccc4c4ccccc4c3c2)c2cccc3c2C2(c4ccccc4-c4ccccc42)c2ccccc2-3)c1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
GGPS1 O95749 1/20 0.37
PRKDC P78527 2/20 0.35
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19218387 0.93 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL19218374 0.93 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2
SCHEMBL19218384 0.92 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2
SCHEMBL19218586 0.90 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL19218377 0.89 ALOX5 (0.37) ALOX5GGPS1PRKDC
SCHEMBL17804817 0.89 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL19218373 0.89 HCRTR1 (0.33) ALOX5PRKDC
SCHEMBL19218383 0.89
SCHEMBL19218385 0.89 ALOX5 (0.40) ALOX5GGPS1PRKDC
SCHEMBL19218380 0.88 HSP90AA1 (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound H1-10, H1-0, H1-4 ALOX5 2357/4885GGPS1 4163/4885PRKDC 4747/4885
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, LEF1, PIEZO1 ALOX5 1199/4885GGPS1 3204/4885PRKDC 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.