SCHEMBL192189

SCHEMBL192189

C=C(C(=O)O)C(NC)(NC)NC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995427 0.76 TDP1 (0.41)
SCHEMBL19305558 0.76 TET2 (0.33) TET2
SCHEMBL1487712 0.69 TSHR (0.39)
SCHEMBL23950 0.67
SCHEMBL2137763 0.67 TET2 (0.39) TET2
SCHEMBL6757384 0.65
SCHEMBL9746099 0.65
SCHEMBL4652781 0.65
Methacrylic Acid SCHEMBL1025759 0.63
Methacrylic Acid SCHEMBL28516520 0.63 ALDH1A1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951598-B2 Hydrophobically modified cationic acrylate copolymer/polysiloxane blends and use in tissue KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-10-04 US claimed
EP-1558811-A1 HYDROPHOBICALLY MODIFIED CATIONIC ACRYLATE COPOLYMER/POLYSILOXANE BLENDS AND USE IN TISSUE Kimberly-Clark Worldwide, Inc. (US) 2005-08-03 EP claimed
WO-2004044322-A1 HYDROPHOBICALLY MODIFIED CATIONIC ACRYLATE COPOLYMER/POLYSILOXANE BLENDS AND USE IN TISSUE KIMBERLY-CLARK WORLDWIDE, INC. (US) 2004-05-27 WO claimed
US-20040086727-A1 Hydrophobically modified cationic acrylate copolymer/polysiloxane blends and use in tissue KIMBERLY-CLARK WORLDWIDE, INC. 2004-05-06 US claimed
EP-1573128-B1 WIPING PRODUCTS HAVING A LOW COEFFICIENT OF FRICTION IN THE WET STATE AND PROCESS FOR PRODUCING SAME KIMBERLY CLARK CO (US) 2012-01-04 EP disclosed
EP-1558809-B1 LOW SLOUGH TISSUE PRODUCTS AND METHOD FOR MAKING SAME KIMBERLY CLARK CO (US) 2011-05-18 EP disclosed
US-7794565-B2 Method of making low slough tissue products KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-09-14 US disclosed
US-20090155358-A1 PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING HYPNOTIC AGENTS IN MODIFIED-RELEASE FORMS AND THE PROCEDURES TO PREPARE THE MENTIONED FORMULATION GADOR S.A. (AR) 2009-06-18 US disclosed
EP-1962810-A2 PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING HYPNOTIC AGENTS IN MODIFIED-RELEASE FORMS AND THE PROCEDURES TO PREPARE THE MENTIONED FORMULATIONS GADOR S.A. (AR) 2008-09-03 EP disclosed
US-20080185114-A1 Method of making low slough tissue products KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-08-07 US disclosed
EP-1147145-B1 SYNTHETIC POLYMERS HAVING HYDROGEN BONDING CAPABILITY AND CONTAINING POLYSILOXANE MOIETIES KIMBERLY CLARK CO (US) 2007-12-26 EP disclosed
WO-2007065625-A2 PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING HYPNOTIC AGENTS IN MODIFIED-RELEASE FORMS AND THE PROCEDURES TO PREPARE THE MENTIONED FORMULATIONS GADOR S.A. (AR) 2007-06-14 WO disclosed
EP-1161467-A1 MODIFIED VINYL POLYMERS CONTAINING AMPHIPHILIC HYDROCARBON MOIETIES Kimberly-Clark Worldwide, Inc. (US) 2001-12-12 EP disclosed
EP-1147145-A1 SYNTHETIC POLYMERS HAVING HYDROGEN BONDING CAPABILITY AND CONTAINING POLYSILOXANE MOIETIES Kimberly-Clark Worldwide, Inc. (US) 2001-10-24 EP disclosed
US-6287418-B1 PAPER SHEET CONTAINING STRENGTH AIDS THAT IMPART SOFTNESS; SOFTENERS THAT DO NOT REDUCE STRENGTH; WET STRENGTH KIMBERLY-CLARK WORLDWIDE, INC. 2001-09-11 US disclosed
US-6274667-B1 BLOCK OR GRAFT POLYMER; PAPERMAKING KIMBERLY-CLARK WORLDWIDE, INC. 2001-08-14 US disclosed
US-6224714-B1 VINYL ALCOHOL, ACRYLAMIDE, AND ACRYLIC ACID-TYPE COPOLYMERS; ADDITION-CONDENSATION COPOLYMERS; WET AND DRY STRENGTH KIMBERLY-CLARK WORLDWIDE, INC. 2001-05-01 US disclosed
WO-2000043428-A1 MODIFIED VINYL POLYMERS CONTAINING AMPHIPHILIC HYDROCARBON MOIETIES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-07-27 WO disclosed
WO-2000043429-A1 SYNTHETIC POLYMERS HAVING HYDROGEN BONDING CAPABILITY AND CONTAINING ALIPHATIC HYDROCARBON MOIETIES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-07-27 WO disclosed
WO-2000043440-A1 SYNTHETIC POLYMERS HAVING HYDROGEN BONDING CAPABILITY AND CONTAINING POLYSILOXANE MOIETIES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155358-A1 PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING HYPNOTIC AGENTS IN MODIFIED-RELEASE FORMS AND THE PROCEDURES TO PREPARE THE MENTIONED FORMULATION CRH, SLC6A11, CRHR2 TET2 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.