SCHEMBL19219086

SCHEMBL19219086

FC(F)(F)c1ccc(-c2cc(-c3ccc(-c4ccncc4)cc3)ncn2)cc1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.68
ABL1 P00519 3/20 0.66
BCR P11274 3/20 0.66
TRPV1 Q8NER1 3/20 0.47
FAAH O00519 1/20 0.45
TOP1 P11387 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4717327 0.91 ABL1 (0.57) KIF11ABL1BCRTRPV1FAAH
SCHEMBL17694993 0.87 MAPT (0.52) KIF11ABL1BCR
SCHEMBL17694984 0.87 MAPT (0.52) KIF11ABL1BCR
SCHEMBL13410613 0.82 KIF11 (1.00) KIF11ABL1BCR
SCHEMBL17694991 0.82 ABL1 (0.50) ABL1BCR
SCHEMBL931294 0.82 KIF11 (1.00) KIF11ABL1BCR
SCHEMBL17694989 0.82 KIF11 (0.68) KIF11ABL1BCRTOP1
SCHEMBL4659183 0.81 KIF11 (0.61) KIF11ABL1BCRTRPV1TOP1
SCHEMBL1011817 0.80 ABL1 (0.51) KIF11ABL1BCRTRPV1FAAH
SCHEMBL12943121 0.80 ABL1 (1.00) ABL1BCRTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9932522-B2 Electrochromic compound, electrochromic composition, display element, and dimming element RICOH COMPANY, LTD. (JP) 2018-04-03 US disclosed
US-9932522-B2 Electrochromic compound, electrochromic composition, display element, and dimming element RICOH COMPANY, LTD. (JP) 2018-04-03 US disclosed
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-10 US disclosed
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT EMC2, EMC1, KCNB2 KIF11 2996/4885ABL1 1966/4885BCR 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.