SCHEMBL19219115

SCHEMBL19219115

CCCCCCCCCCCCCCCCC(C)OCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.48
OPRM1 P35372 1/20 0.42
FAAH O00519 5/20 0.42
EPHX2 P34913 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
SPHK1 Q9NYA1 1/20 0.40
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018867 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL690816 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL9136425 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL10350856 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL17253503 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL4022359 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL3039218 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL7082641 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL11673316 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1
SCHEMBL11631045 1.00 DNM1 (0.48) DNM1OPRM1FAAHEPHX2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10335420-B2 Nanoparticle-based tumor-targeted drug delivery THE SCRIPPS RESEARCH INSTITUTE (US) 2019-07-02 US disclosed
US-20170224838-A1 NANOPARTICLE-BASED TUMOR-TARGETED DRUG DELIVERY THE SCRIPPS RESEARCH INSTITUTE (US) 2017-08-10 US disclosed
US-20170224838-A1 NANOPARTICLE-BASED TUMOR-TARGETED DRUG DELIVERY THE SCRIPPS RESEARCH INSTITUTE (US) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170224838-A1 NANOPARTICLE-BASED TUMOR-TARGETED DRUG DELIVERY LGMN, LAMP1, LNPEP DNM1 1534/4885OPRM1 2410/4885FAAH 1664/4885
US-10335420-B2 Nanoparticle-based tumor-targeted drug delivery LGMN, LAMP1, LNPEP DNM1 1534/4885OPRM1 2410/4885FAAH 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.