SCHEMBL192197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2668082	0.89	ABL1 (0.40)	NPC1KMT2ARAB9AMEN1GAA
	SCHEMBL4306008	0.86	RAB9A (0.46)	NPC1KMT2ARAB9AMEN1GAA
	SCHEMBL12305692	0.82	GCK (0.43)	KMT2ARAB9AMEN1KCNN1KCNN2
	SCHEMBL190466	0.81	NPC1 (0.57)	NPC1KMT2ARAB9AMEN1GAA
	SCHEMBL12305691	0.81	GCK (0.46)	NPC1KMT2ARAB9AMEN1CASP3
	Hydrochloric Acid SCHEMBL190938	0.81	GCK (0.42)	KMT2ARAB9AMEN1KCNN1KCNN2
	SCHEMBL2668016	0.81	RAB9A (0.44)	NPC1KMT2ARAB9AMEN1GAA
	Hydrochloric Acid SCHEMBL191739	0.80	GCK (0.45)	NPC1KMT2ARAB9AMEN1CASP3
	SCHEMBL2739973	0.79	TRPV4 (0.47)	NPC1KMT2ARAB9AMEN1GAA
	SCHEMBL190584	0.75	NPC1 (0.45)	NPC1KMT2ARAB9AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.