Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15279597 | 0.74 | HDAC3 (0.46) | MAOBCYP1A2TSHRNFKB1TERT | |
| SCHEMBL14117366 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTNPC1RAB9ALMNA | |
| SCHEMBL24454271 | 0.73 | CSNK2A1 (0.51) | SMN1; SMN2HTTRAB9ALMNAKDM4E | |
| SCHEMBL25014999 | 0.73 | KDM4E (0.55) | MAOBNPC1RAB9ALMNACYP1A2 | |
| SCHEMBL26225948 | 0.73 | THRB (0.40) | SMN1; SMN2HTTNPC1RAB9ALMNA | |
| SCHEMBL1003874 | 0.72 | POLB (0.47) | SMN1; SMN2HTTMAOBNPC1RAB9A | |
| SCHEMBL28171668 | 0.72 | KDM4E (0.47) | LMNAKDM4E | |
| SCHEMBL8604816 | 0.72 | NR5A2 (0.54) | SMN1; SMN2MAOBCYP1A2TSHRNFKB1 | |
| SCHEMBL11230535 | 0.71 | HPGD (0.64) | SMN1; SMN2HTTNPC1RAB9ATSHR | |
| SCHEMBL13962498 | 0.71 | SIGMAR1 (0.55) | LMNATSHRHDAC1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724434-B2 | Lysine oligomer derivative and cartilage tissue marker made thereof | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2017-08-08 | — | — | US | disclosed |